TC-5115
TC-5115 is a potent and selective inhibitor of the MLL1 methyltransferase (IC50 = 16 nM), which catalyzes histone H3 lysine 4 methylation. This compound is a valuable research tool for investigating MLL-driven leukemogenesis and has demonstrated efficacy in preclinical in vitro and in vivo models of MLL-rearranged acute leukemia.
Product Specifications
CAS Number
2458182-10-8
Field of Research
Epigenetics & Chromatin
Purity
99.44% (May vary between batches)
Smiles
O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@H] (CN (CC4CN (CC5=CC=CS5) C4) CC[C@@H] (C (O) =O) N) [C@H]1O
Molecular Formula
C23H32N8O5S
Molecular Weight
532.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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