Hemopressin (human, mouse)

Hemopressin is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin exerts antinociceptive action in inflammatory pain models[1][2].

Product Specifications

CAS Number

[1314035-51-2]

UNSPSC

12352209

Target

Cannabinoid Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hemopressin-human-mouse.html

Purity

99.95

Solubility

H2O : ≥ 16.67 mg/mL

Smiles

O=C(O)[C@H](CC1=CNC=N1)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@H](CC2=CC=CC=C2)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H]3NCCC3)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C50H79N13O12

Molecular Weight

1054.24

References & Citations

[1]Garron T Dodd, et al. The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food intake in rats and mice. J Neurosci. 2010 May 26;30 (21) :7369-76.|[2]Elaine F Toniolo, et al. Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats. Peptides. 2014 Jun;56:125-31.