GS-441524 HCl
GS-441524 is the active metabolite of Remdesivir and a potent nucleoside analog inhibitor of viral RNA-dependent RNA polymerase. It demonstrates strong antiviral activity against feline infectious peritonitis virus (FIPV) both in vitro (e.g., CRFK cells and feline macrophages) and in vivo, with an EC50 of 0.78 μM, and shows low cytotoxicity at concentrations up to 100 μM.
Product Specifications
CAS Number
2378280-82-9
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology
Smiles
C (#N) [C@]1 (O[C@H] (CO) [C@@H] (O) [C@H]1O) C=2N3C (=CC2) C (N) =NC=N3.Cl
Molecular Formula
C12H14ClN5O4
Molecular Weight
327.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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