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G108

G108 is a selective small molecule inhibitor of human cyclic GMP-AMP synthase (cGAS) . It is a valuable research tool for investigating cGAS-mediated innate immune pathways in autoimmune and inflammatory diseases, applicable in both cellular and animal model studies.

Product Specifications

CAS Number

2369750-66-1

Product Name Alternative

G108, G-108, G 108, cGAS, CNP 520, CNP-520, Umibecestat HCl, Umibecestat hydrochloride

Field of Research

Immunology & Inflammation

Purity

99.13% (May vary between batches)

Solubility

H2O:120 mg/mL (328.58 mM)

Smiles

O=C (N1CC=2C=3C (=CC (Cl) =C (Cl) C3NC2CC1) C=4C=NNC4) CO

Molecular Formula

C16H14Cl2N4O2

Molecular Weight

365.21

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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