XL-188
XL-188 is a potent and selective USP7 inhibitor with low nanomolar IC50 values, promoting HDM2 degradation and p53/p21 stabilization. This tool compound is used in oncology research to study the p53 pathway in cellular and biochemical assays.
Product Specifications
CAS Number
2305045-76-3
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Smiles
O=C1C=2C (=CC (NC (CCN3CCN (C) CC3) =O) =CC2) N=CN1CC4 (O) CCN (C (C[C@@H] (C) C5=CC=CC=C5) =O) CC4
Molecular Formula
C32H42N6O4
Molecular Weight
574.71
Storage Conditions
-20°C
Notes
For research use only.
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