ADA-07
ADA-07 is a small molecule inhibitor that targets the ATP-binding site of TOPK, blocking its kinase function. This inhibition suppresses the SUV-induced phosphorylation of MAPK pathways (ERK1/2, p38, JNK) and downstream AP-1 activity. It is a valuable research tool for studying TOPK signaling in cancer and inflammation models, both in vitro and in vivo.
Product Specifications
CAS Number
2252153-94-7
Field of Research
Metabolism Research
Smiles
N (O) =C1C2=CC (C34CC5CC (C3) CC (C4) C5) =CC=C2NC1=O
Molecular Formula
C18H20N2O2
Molecular Weight
296.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
127072-AP 100 µL
G3BP1 (Ras GTPase-activating Protein-binding Protein 1, G3BP-1, ATP-dependent DNA Helicase VIII, hDH VIII, GAP SH3 Domain-binding Protein 1, G3BP) (AP) discontinued
Sign In for Pricing
View Details 
