ADA-07
ADA-07 is a small molecule inhibitor that targets the ATP-binding site of TOPK, blocking its kinase function. This inhibition suppresses the SUV-induced phosphorylation of MAPK pathways (ERK1/2, p38, JNK) and downstream AP-1 activity. It is a valuable research tool for studying TOPK signaling in cancer and inflammation models, both in vitro and in vivo.
Product Specifications
CAS Number
2252153-94-7
Field of Research
Metabolism Research
Smiles
N (O) =C1C2=CC (C34CC5CC (C3) CC (C4) C5) =CC=C2NC1=O
Molecular Formula
C18H20N2O2
Molecular Weight
296.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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