BMS-986313
BMS-986313 is a potent and selective inverse agonist of the RORγt nuclear receptor, demonstrating an EC50 of 3.6 nM in biochemical assays and 50 nM in cellular reporter assays. This small molecule is a valuable research tool for investigating Th17 cell biology and autoimmune pathologies in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
2226319-10-2
Smiles
S (=O) (=O) ([C@]12C=3C (=CC (C (C (F) (F) F) (C (F) (F) F) F) =CC3) CC[C@]1 ([C@H] (NC (C (C) (C) O) =O) CC2) [H]) C4=CC=C (F) C=C4
Molecular Formula
C26H25F8NO4S
Molecular Weight
599.53
Storage Conditions
-20°C
Notes
For research use only.
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