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GSK3491943

GSK3491943 is a highly potent and selective TRPV4 channel inhibitor (IC50 = 3.2 nM) . Its application in research spans cardiovascular and pulmonary biology, with studies investigating its therapeutic potential for conditions like heart failure and pulmonary edema in both cellular and animal models.

Product Specifications

CAS Number

2215853-96-4

Smiles

O ([C@@H]1[C@@] (CO) (O) CN (S (=O) (=O) C2=C (Cl) C=C (C#N) C=C2) C1) C3=CC=C (Cl) C=C3

Molecular Formula

C18H16Cl2N2O5S

Molecular Weight

443.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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