AZD-6126
AZD6126 (ANG-453) is a water-soluble phosphate prodrug converted in vivo to N-acetylcolchinol, a tubulin-binding agent. It acts as a vascular disrupting agent, selectively targeting and destabilizing the tumor vasculature to induce endothelial apoptosis, vessel occlusion, and tumor necrosis in preclinical solid tumor models.
Product Specifications
CAS Number
219923-05-4
Smiles
O (C) C1=C2C=3C ([C@@H] (NC (C) =O) CCC2=CC (OC) =C1OC) =CC (OP (=O) (O) O) =CC3
Molecular Formula
C20H24NO8P
Molecular Weight
437.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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