USP7-IN-4
USP7-IN-4 (ALM4) is a potent and selective non-competitive USP7 inhibitor with a 6 nM IC50. It stabilizes p53 and induces p21, leading to anti-proliferative effects in cancer cell lines such as RS4;11 leukemia cells (EC50 = 2.0 nM) . This compound is a valuable chemical probe for studying the USP7-MDM2-p53 pathway in oncology research.
Product Specifications
CAS Number
2196243-57-7
Product Name Alternative
AD-04, AMP 423., AMP-423, USP7 inhibitor ALM4, USP7-IN-2, USP7-IN-4
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry
Purity
98.27% (May vary between batches)
Smiles
CN1C (=C2C (C (=O) N (CC3 (O) CCN (C (C[C@@H] (C) C4=CC=CC=C4) =O) CC3) C=N2) =N1) C5=CC=C (CN) C=C5
Molecular Formula
C29H34N6O3
Molecular Weight
514.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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