VTP50469 mesylate
VTP-50469 is a potent, selective, and orally bioavailable Menin-MLL1 interaction inhibitor. It demonstrates efficacy in preclinical models of MLL-rearranged and NPM1-mutant leukemias, showing selective cytotoxicity in relevant cell lines and anti-leukemic activity in vivo.
Product Specifications
CAS Number
2169919-27-9
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
CS (O) (=O) =O.CS (O) (=O) =O.CC (C) N (C (C) C) C (=O) c1cc (F) ccc1Oc1cncnc1N1CC2 (C1) CCN (C[C@H]1CC[C@@H] (CC1) NS (C) (=O) =O) CC2
Molecular Formula
C33H51FN6O7S2
Molecular Weight
726.9244
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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