MC-70 hydrochloride
MC-70 hydrochloride is a potent and selective P-glycoprotein (P-gp) inhibitor, demonstrating high potency in Caco-2 and MDR1 assays with EC50 values of 0.05 μM and 0.69 μM, respectively, while showing significantly weaker activity against BCRP. This selectivity profile makes it a valuable research tool for investigating multidrug resistance in cancer and for enhancing drug bioavailability in both cellular and animal models.
Product Specifications
CAS Number
2108830-71-1
Smiles
Cl.COc1cc2CCN (Cc3ccc (cc3) -c3ccc (O) cc3) Cc2cc1OC
Molecular Formula
C24H26ClNO3
Molecular Weight
411.926
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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