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MC-70 hydrochloride

MC-70 hydrochloride is a potent and selective P-glycoprotein (P-gp) inhibitor, demonstrating high potency in Caco-2 and MDR1 assays with EC50 values of 0.05 μM and 0.69 μM, respectively, while showing significantly weaker activity against BCRP. This selectivity profile makes it a valuable research tool for investigating multidrug resistance in cancer and for enhancing drug bioavailability in both cellular and animal models.

Product Specifications

CAS Number

2108830-71-1

Smiles

Cl.COc1cc2CCN (Cc3ccc (cc3) -c3ccc (O) cc3) Cc2cc1OC

Molecular Formula

C24H26ClNO3

Molecular Weight

411.926

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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