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Pidnarulex HCl

Pidnarulex HCl (CX-5461) is a selective RNA polymerase I inhibitor that induces p53-mediated apoptosis in cancer cells via nucleolar stress, without causing DNA damage. It has demonstrated potent in vitro cytotoxicity and robust oral efficacy in vivo across various cancer models, including hematological and solid tumors.

Product Specifications

CAS Number

2101314-20-7

Smiles

Cl.CN1CCCN (CC1) c1ccc2c (n1) n1c3ccccc3sc1c (C (=O) NCc1cnc (C) cn1) c2=O

Molecular Formula

C27H28ClN7O2S

Molecular Weight

550.08

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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