Pidnarulex HCl
Pidnarulex HCl (CX-5461) is a selective RNA polymerase I inhibitor that induces p53-mediated apoptosis in cancer cells via nucleolar stress, without causing DNA damage. It has demonstrated potent in vitro cytotoxicity and robust oral efficacy in vivo across various cancer models, including hematological and solid tumors.
Product Specifications
CAS Number
2101314-20-7
Smiles
Cl.CN1CCCN (CC1) c1ccc2c (n1) n1c3ccccc3sc1c (C (=O) NCc1cnc (C) cn1) c2=O
Molecular Formula
C27H28ClN7O2S
Molecular Weight
550.08
Storage Conditions
-20°C
Notes
For research use only.
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