LEO-134310
LEO 134310 is a potent, non-steroidal, and selective glucocorticoid receptor agonist designed for topical application, with an EC50 of 14 nM. It is a valuable research tool for investigating GR-mediated pathways in dermatological diseases, suitable for both in vitro binding studies and in vivo models of skin inflammation.
Product Specifications
CAS Number
2089130-74-3
Field of Research
Metabolism Research
Smiles
[C@H] (OC1=CC=C (C (O[C@@H]2CN (C (=O) [C@@H]3CC (=O) OC3) CCC2) =O) C=C1) ([C@@H] (NC (=O) [C@H]4CCCO4) C) C5=CC=C (C=C5) C6CC6
Molecular Formula
C34H40N2O8
Molecular Weight
604.69
Storage Conditions
-20°C
Notes
For research use only.
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