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NK314

NK314 is a synthetic benzo[c]phenanthridine alkaloid with potent antitumor activity, functioning as a topoisomerase II poison that induces rapid, proteinase K-independent DNA cleavage. Its mechanism and efficacy have been studied in vitro and in vivo, supporting its application in cancer research, particularly in investigating DNA damage and chemotherapeutic strategies.

Product Specifications

CAS Number

208237-49-4

Field of Research

Molecular Biology

Smiles

[Cl-].COc1ccc2c (c3CCC[n+]3c3c4cc5OCOc5cc4ccc23) c1O

Molecular Formula

C22H20ClNO4

Molecular Weight

397.85

Storage Conditions

-20°C

Notes

For research use only.

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