JPI-547 HCl
JPI-547 (NOV 1402) is an orally active dual PARP1/2 and Tankyrase1/2 inhibitor. It exhibits single-agent anti-tumor efficacy in BRCA-deficient models and shows synergistic activity in combination with chemotherapy or immune checkpoint inhibitors in preclinical in vivo studies.
Product Specifications
CAS Number
2055357-65-6
Smiles
Cl.Cl.O=c1[nH]c2cc (CN3CCN (CC3) c3ccc (cn3) C#N) ccc2c2NCCCc12
Molecular Formula
C23H26Cl2N6O
Molecular Weight
473.402
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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