Istaroxime oxalate
Istaroxime (PST-2744) is a novel inotropic agent that acts by inhibiting Na+/K+ ATPase, leading to increased intracellular sodium and calcium. It further enhances cardiac contractility by sensitizing the sarcoplasmic reticulum calcium release and modulating L-type calcium channels. This compound is utilized in research models of acute heart failure to study myocardial calcium handling and contractile function.
Product Specifications
CAS Number
203737-94-4
Field of Research
Pharmacology & Drug Discovery
Smiles
OC (=O) C (O) =O.[H][C@@]12CCC (=O) [C@@]1 (C) CC[C@@]1 ([H]) [C@@]2 ([H]) CC (=O) [C@@]2 ([H]) CC (CC[C@]12C) =NOCCN
Molecular Formula
C23H34N2O7
Molecular Weight
450.53
Storage Conditions
-20°C
Notes
For research use only.
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