WS-691
WS-691 is a potent, orally bioavailable ABCB1 modulator that reverses multidrug resistance in vitro and in vivo. It inhibits ABCB1-mediated drug efflux, increasing intracellular paclitaxel accumulation and chemosensitivity in resistant cancer models like SW620/Ad300 cells without observed toxicity.
Product Specifications
CAS Number
2035417-32-2
Smiles
N (C=1N2C (=NC (SCC=3NC=4C (N3) =CC=CC4) =N2) N=C (C) C1) C5=CC=C (F) C=C5
Molecular Formula
C20H16FN7S
Molecular Weight
405.45
Storage Conditions
-20°C
Notes
For research use only.
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