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WS-691

WS-691 is a potent, orally bioavailable ABCB1 modulator that reverses multidrug resistance in vitro and in vivo. It inhibits ABCB1-mediated drug efflux, increasing intracellular paclitaxel accumulation and chemosensitivity in resistant cancer models like SW620/Ad300 cells without observed toxicity.

Product Specifications

CAS Number

2035417-32-2

Smiles

N (C=1N2C (=NC (SCC=3NC=4C (N3) =CC=CC4) =N2) N=C (C) C1) C5=CC=C (F) C=C5

Molecular Formula

C20H16FN7S

Molecular Weight

405.45

Storage Conditions

-20°C

Notes

For research use only.

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