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DHA-paclitaxel

DHA-paclitaxel (Taxoprexin) is a prodrug that conjugates paclitaxel to the fatty acid DHA for targeted tumor delivery. It inhibits microtubule disassembly and Bcl-2 function, blocking cell division and inducing apoptosis. This agent shows enhanced pharmacokinetics and antitumor efficacy in preclinical in vivo cancer models.

Product Specifications

CAS Number

199796-52-6

Field of Research

Pharmacology & Drug Discovery

Smiles

O (C (C) =O) [C@]12[C@]3 ([C@H] (OC (=O) C4=CC=CC=C4) [C@@]5 (O) C (C) (C) C ([C@@H] (OC (C) =O) C (=O) [C@]3 (C) [C@@H] (O) C[C@]1 (OC2) [H]) =C (C) [C@@H] (OC ([C@@H] ([C@@H] (NC (=O) C6=CC=CC=C6) C7=CC=CC=C7) OC (CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC) =O) =O) C5) [H]

Molecular Formula

C69H81NO15

Molecular Weight

1164.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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