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Bomedemstat ditosylate

Bomedemstat ditosylate (IMG-7289 ditosylate) is an oral LSD1 inhibitor with antitumor activity. It is used in research on myeloproliferative neoplasms and myelofibrosis, where it has been shown to inhibit cancer cell proliferation and enhance PD-1 blockade efficacy in preclinical SCLC models.

Product Specifications

CAS Number

1990504-72-7

Product Name Alternative

IMG-7289 ditosylate, MK-3543 ditosylate, LSD1, GLX-481372, GLX 481372, Histone Demethylase, HistoneDemethylase, Bomedemstat, Bomedemstat Ditosylate, Apoptosis

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

99.05% (May vary between batches)

Solubility

DMSO:80 mg/mL (92.59 mM)

Smiles

Cc1ccc (cc1) S (O) (=O) =O.Cc1ccc (cc1) S (O) (=O) =O.[H][C@]1 (C[C@H]1NCCC[C@H] (NC (=O) c1ccc (cc1) -n1ccnn1) C (=O) N1CCN (C) CC1) c1ccc (F) cc1

Molecular Formula

C42H50FN7O8S2

Molecular Weight

864.02

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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