14- (Fmoc-amino) -tetradecanoic acid

This compound serves as a versatile PROTAC linker, featuring a terminal carboxylic acid and an Fmoc-protected amine on a tetradecane spacer. The Fmoc group is readily cleaved to expose a primary amine for conjugation, while the acid can be activated to form amide bonds. It is widely used in chemical biology for constructing heterobifunctional degraders for both in vitro and in vivo target validation studies.