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PF-06463922 acetate

PF-06463922 acetate is a brain-penetrant, dual ALK/ROS1 inhibitor effective against crizotinib-resistant mutants. It is a research compound for studying oncogenic kinase signaling in NSCLC, with demonstrated activity in both cellular assays and preclinical in vivo models.

Product Specifications

CAS Number

1924207-18-0

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

CC (O) =O.C[C@H]1Oc2cc (cnc2N) -c2c (CN (C) C (=O) c3ccc (F) cc13) nn (C) c2C#N

Molecular Formula

C23H23FN6O4

Molecular Weight

466.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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