PF-06463922 acetate
PF-06463922 acetate is a brain-penetrant, dual ALK/ROS1 inhibitor effective against crizotinib-resistant mutants. It is a research compound for studying oncogenic kinase signaling in NSCLC, with demonstrated activity in both cellular assays and preclinical in vivo models.
Product Specifications
CAS Number
1924207-18-0
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
CC (O) =O.C[C@H]1Oc2cc (cnc2N) -c2c (CN (C) C (=O) c3ccc (F) cc13) nn (C) c2C#N
Molecular Formula
C23H23FN6O4
Molecular Weight
466.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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