JNJ-61803534
JNJ-61803534 is a potent and orally bioavailable RORγt inverse agonist. It inhibits IL-17A production in human Th17 cells with an IC50 of 9.6 nM, demonstrating anti-inflammatory activity. This compound is a valuable tool for researching Th17-driven pathologies such as psoriasis and autoimmune diseases in both cellular and animal models.
Product Specifications
CAS Number
1917306-14-9
Field of Research
Metabolism Research
Smiles
C[C@@H]1CCCN1C (=O) c1nc (sc1-c1ccc (c (Cl) c1Cl) C (O) (C (F) (F) F) C (F) (F) F) C (=O) NCC (C) (C) O
Molecular Formula
C23H23Cl2F6N3O4S
Molecular Weight
622.41
Storage Conditions
-20°C
Notes
For research use only.
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