Pamiparib hydrate
Pamiparib (BGB-290) is a potent and selective PARP inhibitor that disrupts DNA repair via the base-excision repair pathway, leading to genomic instability and apoptosis. It is widely used in cancer research to study synthetic lethality in BRCA-deficient models and to potentiate the effects of DNA-damaging agents in both in vitro and in vivo experiments.
Product Specifications
CAS Number
1858211-28-5
Smiles
O.C[C@]12CCCN1Cc1n[nH]c (=O) c3cc (F) cc4[nH]c2c1c34
Molecular Formula
C16H21FN4O4
Molecular Weight
352.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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