DDR1-IN-1 HCl
DDR1-IN-1 dihydrochloride is a potent and selective inhibitor of the discoidin domain receptor 1 (DDR1) tyrosine kinase (IC50 = 105 nM), showing 4-fold selectivity over DDR2. This tool compound is useful for investigating DDR1's role in fibrosis and cancer progression in both cellular and animal models.
Product Specifications
CAS Number
1780303-76-5
Field of Research
Signal Transduction
Smiles
Cl.Cl.O=C (NC1=CC=C (C (OC2=CC=C3NC (=O) CC3=C2) =C1) C) C4=CC=C (C (=C4) C (F) (F) F) CN5CCN (CC) CC5
Molecular Formula
C30H33Cl2F3N4O3
Molecular Weight
625.51
Storage Conditions
-20°C
Notes
For research use only.
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