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PD-149163

PD-149163 is a selective, brain-penetrant agonist of the Neurotensin NTR1 receptor. It demonstrates pro-cognitive, antipsychotic, and anxiolytic properties in preclinical models, attributed to its ability to counteract sensorimotor gating deficits induced by serotonergic and adrenergic agents. This small molecule is utilized in neuroscience research for investigating neuropsychiatric disorders in both in vitro and in vivo experimental systems.

Product Specifications

CAS Number

169528-11-4

Smiles

C ([C@H] (NC (=O) [C@H]1N (C ([C@@H] (NC[C@H] (CCCCN) N) CCCCN) =O) CCC1) C (N[C@H] (C (N[C@H] (C (OCC) =O) CC (C) C) =O) C (C) (C) C) =O) C=2C=3C (NC2) =CC=CC3

Molecular Formula

C42H71N9O6

Molecular Weight

798.07

Storage Conditions

-20°C

Notes

For research use only.

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