PD-149163
PD-149163 is a selective, brain-penetrant agonist of the Neurotensin NTR1 receptor. It demonstrates pro-cognitive, antipsychotic, and anxiolytic properties in preclinical models, attributed to its ability to counteract sensorimotor gating deficits induced by serotonergic and adrenergic agents. This small molecule is utilized in neuroscience research for investigating neuropsychiatric disorders in both in vitro and in vivo experimental systems.
Product Specifications
CAS Number
169528-11-4
Smiles
C ([C@H] (NC (=O) [C@H]1N (C ([C@@H] (NC[C@H] (CCCCN) N) CCCCN) =O) CCC1) C (N[C@H] (C (N[C@H] (C (OCC) =O) CC (C) C) =O) C (C) (C) C) =O) C=2C=3C (NC2) =CC=CC3
Molecular Formula
C42H71N9O6
Molecular Weight
798.07
Storage Conditions
-20°C
Notes
For research use only.
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