PAT-347
PAT-347 is a potent small molecule inhibitor of Autotaxin (ATX), the enzyme that produces lysophosphatidic acid (LPA) from lysophosphatidylcholine. By blocking this key enzymatic step, it disrupts the ATX-LPA signaling axis, a validated target for research in fibrosis, cancer biology, and inflammatory diseases, as evidenced in various in vitro and in vivo studies.
Product Specifications
CAS Number
1689554-51-5
Field of Research
Metabolism Research
Smiles
C (CN1C=2C (C (SC3=C (F) C (C (O) =O) =CC=C3) =C1C) =CC=C (Cl) C2F) (=O) N4CC5 (C=6C4=CC=CC6) CC5
Molecular Formula
C28H21ClF2N2O3S
Molecular Weight
538.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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