KB-R7785
KB-R7785 is a novel small molecule inhibitor targeting ADAM12 and MMPs. It improves cardiac function in TAC models by blocking HB-EGF shedding and enhances insulin sensitivity via suppression of TNF-α, making it a useful research tool for studying heart failure and diabetes-related pathways.
Product Specifications
CAS Number
168158-16-5
Field of Research
Protein Biochemistry
Smiles
[C@@H] (NC ([C@@H] ([C@@H] (C (NO) =O) C) CC (C) C) =O) (C (NC) =O) C1=CC=CC=C1
Molecular Formula
C18H27N3O4
Molecular Weight
349.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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