PF-05214030
PF-05214030 is a potent and selective TRPV4 channel antagonist, exhibiting IC50 values of 4 nM and 27 nM against human and rat TRPV4, respectively. This tool compound is widely used in vitro and in vivo to investigate TRPV4's role in pain, pulmonary function, and osmoregulation.
Product Specifications
CAS Number
1669444-50-1
Field of Research
Pharmacology & Drug Discovery
Smiles
S (=O) (=O) (N1CC (COC2=CC (F) =C (C#N) C=C2) (O) C1) C3=C (Cl) C=C (Cl) C=C3
Molecular Formula
C17H13Cl2FN2O4S
Molecular Weight
431.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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