Mevidalen HBA
Mevidalen (LY3154207) is a potent and selective D1 dopamine receptor positive allosteric modulator (PAM) with minimal agonist activity. Its distinct pharmacological profile, lacking bell-shaped dose-response or tachyphylaxis, supports its clinical development for Lewy body dementia. Research applications include investigating D1 receptor neurobiology in both in vitro binding assays and in vivo preclinical models of cognition and movement.
Product Specifications
CAS Number
1638669-32-5
Smiles
OC (=O) c1ccc (O) cc1.C[C@@H]1N ([C@@H] (CO) Cc2c (CCC (C) (C) O) cccc12) C (=O) Cc1c (Cl) cccc1Cl
Molecular Formula
C31H35Cl2NO6
Molecular Weight
588.52
Storage Conditions
-20°C
Notes
For research use only.
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