TOP1362
TOP1362 is a narrow-spectrum kinase inhibitor targeting p38α, Syk, Src, and Lck. It demonstrates potent anti-inflammatory effects in cellular models and in vivo endotoxin-induced uveitis (EIU), reducing cytokine release and inflammatory cell infiltration with efficacy comparable to dexamethasone, supporting research for ocular inflammatory disorders.
Product Specifications
CAS Number
1630203-25-6
Smiles
O (C=1C2=C (C (NC (NC3=C (OC) C (NS (C) (=O) =O) =CC (C (C) (C) C) =C3) =O) =CC1) C=CC=C2) C=4C=C (NC5=CC (C (NCCCN6CCOCC6) =O) =CC (OC) =C5) N=CC4
Molecular Formula
C43H51N7O8S
Molecular Weight
825.97
Storage Conditions
-20°C
Notes
For research use only.
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