PH11
PH11 is a novel small molecule inhibitor of Focal Adhesion Kinase (FAK) . It overcomes TRAIL resistance in cancer cells, such as PANC-1 pancreatic carcinoma, by suppressing FAK and the PI3K/AKT pathways to downregulate c-FLIP and restore apoptosis. This mechanism supports its investigation in both in vitro and in vivo oncology research models.
Product Specifications
CAS Number
1627843-95-1
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
N (C=1N2C (N=C (NC3=C (C (OC) =O) C=CC=C3) N1) =NC=C2) C4=CC (OC) =C (OC) C (OC) =C4
Molecular Formula
C22H22N6O5
Molecular Weight
450.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Rabbit Polyclonal Senataxin Antibody [DyLight 650]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
NB100-57543C 100 µL
Rabbit Polyclonal Senataxin Antibody [DyLight 650]
Sign In for Pricing
View Details 
LV715634 1.0 µg DNA
SYTL1 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details MBS1318999-01 0.02 mg (E-Coli)
Recombinant Bombyx mori Tropomyosin-1
Sign In for Pricing
View Details MBS1318999-02 0.02 mg (Yeast)
Recombinant Bombyx mori Tropomyosin-1
Sign In for Pricing
View Details MBS1318999-03 0.1 mg (E-Coli)
Recombinant Bombyx mori Tropomyosin-1
Sign In for Pricing
View Details