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SF0166

SF0166 is a potent and selective αvβ3 integrin antagonist (IC50 = 0.6 nM) that effectively inhibits cellular adhesion to vitronectin in vitro and demonstrates significant anti-angiogenic activity by reducing pathological neovascularization in mouse models of oxygen-induced retinopathy.

Product Specifications

CAS Number

1621332-91-9

Field of Research

Signal Transduction

Smiles

[C@@H] (CC (O) =O) (N1C (=O) N (CCCC=2NC=3C (=CC2) CCCN3) CC1) C=4C=CC (OC (F) F) =NC4

Molecular Formula

C23H27F2N5O4

Molecular Weight

475.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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