SF0166
SF0166 is a potent and selective αvβ3 integrin antagonist (IC50 = 0.6 nM) that effectively inhibits cellular adhesion to vitronectin in vitro and demonstrates significant anti-angiogenic activity by reducing pathological neovascularization in mouse models of oxygen-induced retinopathy.
Product Specifications
CAS Number
1621332-91-9
Field of Research
Signal Transduction
Smiles
[C@@H] (CC (O) =O) (N1C (=O) N (CCCC=2NC=3C (=CC2) CCCN3) CC1) C=4C=CC (OC (F) F) =NC4
Molecular Formula
C23H27F2N5O4
Molecular Weight
475.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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