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(S) -Enitociclib

(S) -Enitociclib (VIP152) is a potent and selective CDK9 inhibitor that suppresses RNA polymerase II-driven transcription, leading to the downregulation of pro-survival proteins and complete regression of MYC-driven lymphomas in vivo. Its application extends to oncology research, particularly in studying transcription-dependent cancers, with efficacy demonstrated in both cellular and animal models.

Product Specifications

CAS Number

1610408-97-3

Product Name Alternative

CDK9, BMS986126, BMS 986126, VIP 152, VIP152, VIP-152

Field of Research

Cell Biology, Molecular Biology

Purity

98.04% (May vary between batches)

Smiles

COC1=C (C2=C (F) C=NC (NC3=CC (C[S@@] (C) (=N) =O) =CC=N3) =C2) C=CC (F) =C1

Molecular Formula

C19H18F2N4O2S

Molecular Weight

404.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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