AMG151 HCl
ARRY-403 (AMG-151) is an oral allosteric glucokinase activator developed for type 2 diabetes research. It potently activates human GK in vitro, shifting the glucose S0.5 to 0.93 mM, and demonstrates favorable drug-like properties with low DDI potential for experimental studies.
Product Specifications
CAS Number
1609674-80-7
Smiles
Cl.Cl.Cc1ncccc1Oc1cc (Sc2ccccn2) cnc1Nc1nc (ns1) [C@H] (O) CO
Molecular Formula
C20H20Cl2N6O3S2
Molecular Weight
527.439
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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