VUF14480
VUF14480 is a covalent partial agonist that selectively and irreversibly binds to cysteine 98 (Cys3.36) of the human histamine H4 receptor. It demonstrates submicromolar affinity and partial agonism in both G protein signaling and β-arrestin2 recruitment assays, making it a valuable tool compound for investigating H4R pharmacology in vitro.
Product Specifications
CAS Number
1605304-31-1
Smiles
C (=C) C=1N=C (C=C (N1) C2=CC=CC=C2) N3CCN (C) CC3
Molecular Formula
C17H20N4
Molecular Weight
280.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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