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XK469

XK489 is a synthetic quinoxaline phenoxypropionic acid derivative that acts as a selective topoisomerase II-beta inhibitor. Its R (+) enantiomer induces G2/M cell cycle arrest and apoptosis in cancer cells by disrupting MEK/MAPK signaling and activating p53, demonstrating cytotoxic effects in both in vitro and in vivo cancer research models.

Product Specifications

CAS Number

157435-10-4

Smiles

O (C1=NC2=C (N=C1) C=CC (Cl) =C2) C3=CC=C (OC (C (O) =O) C) C=C3

Molecular Formula

C17H13ClN2O4

Molecular Weight

344.75

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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