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Afabicin diolamine

Afabicin (Debio 1450) is a first-in-class prodrug antibiotic that specifically inhibits the FabI enzyme in Staphylococcus species, disrupting bacterial fatty acid synthesis. Its unique mechanism has shown potent in vitro and in vivo activity against staphylococcal infections, including MRSA, in preclinical studies.

Product Specifications

CAS Number

1518800-36-6

Smiles

NCCO.NCCO.CN (Cc1oc2ccccc2c1C) C (=O) \C=C\c1cnc2N (COP (O) (O) =O) C (=O) CCc2c1

Molecular Formula

C27H38N5O9P

Molecular Weight

607.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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