Puromycin (dihydrochloride) (Standard)

Puromycin (dihydrochloride) (Standard) is the analytical standard of Puromycin (dihydrochloride) . This product is intended for research and analytical applications. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis[1].

Product Specifications

CAS Number

[58-58-2]

Product Name Alternative

CL13900 (dihydrochloride) (Standard)

UNSPSC

12352005

Hazard Statement

H302

Target

Antibiotic; Bacterial; Parasite; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/puromycin-dihydrochloride-standard.html

Purity

99.84

Smiles

OC[C@@H]1[C@@H](NC([C@@H](N)CC2=CC=C(OC)C=C2)=O)[C@H]([C@H](N3C=NC4=C3N=CN=C4N(C)C)O1)O.[H]Cl.[H]Cl

Molecular Formula

C22H31Cl2N7O5

Molecular Weight

544.43

Precautions

H302

References & Citations

[1]Nathans D, et al. Puromycin inhibition of protein synthesis: incorporation of puromycin intopeptide chains. Proc Natl Acad Sci U S A. 1964 Apr;51:585-92.|[2]Miyamoto-Sato E, et al. Specific bonding of puromycin to full-length protein at the C-terminus. Nucleic Acids Res. 2000 Mar 1;28 (5) :1176-82.|[3]Schmidt EK, et al. SUnSET, a nonradioactive method to monitor protein synthesis. Nat Methods. 2009 Apr;6 (4) :275-7.