PEN-866
PEN-866 is a novel small molecule conjugate designed for NSCLC research, combining an HSP90 inhibitor with the topoisomerase I inhibitor SN-38 via an esterase-cleavable linker. It has demonstrated potential in suppressing early-stage tumor growth in both in vitro and in vivo preclinical models.
Product Specifications
CAS Number
1472614-83-7
Smiles
C (C) C1=C2C (C=3N (C2) C (=O) C4=C (C3) [C@] (CC) (O) C (=O) OC4) =NC=5C1=CC (OC (=O) N6CCC (CCN7C=8C (C=C7) =CC (=CC8) N9C (=NNC9=O) C%10=CC (C (C) C) =C (O) C=C%10O) CC6) =CC5
Molecular Formula
C49H49N7O9
Molecular Weight
879.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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