Deltarasin HCl
Deltarasin is a high-affinity inhibitor that disrupts the PDEδ-KRAS interaction by occupying a hydrophobic pocket on PDEδ. This inhibition impairs KRAS signaling and cell growth in pancreatic cancer models, and its anti-cancer activity is enhanced when combined with autophagy blockade. It is used in oncology research to study KRAS-driven cancers in both cellular and animal studies.
Product Specifications
CAS Number
1440898-82-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
[C@H] (COC1=CC=C (C=C1) C=2N (CC3=CC=CC=C3) C=4C (N2) =CC=CC4) (N5C (=NC=6C5=CC=CC6) C7=CC=CC=C7) [C@H]8CCNCC8.Cl
Molecular Formula
C40H37N5O.xHCl
Molecular Weight
713.144
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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