Deltarasin HCl
Deltarasin is a high-affinity inhibitor that disrupts the PDEδ-KRAS interaction by occupying a hydrophobic pocket on PDEδ. This inhibition impairs KRAS signaling and cell growth in pancreatic cancer models, and its anti-cancer activity is enhanced when combined with autophagy blockade. It is used in oncology research to study KRAS-driven cancers in both cellular and animal studies.
Product Specifications
CAS Number
1440898-82-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
[C@H] (COC1=CC=C (C=C1) C=2N (CC3=CC=CC=C3) C=4C (N2) =CC=CC4) (N5C (=NC=6C5=CC=CC6) C7=CC=CC=C7) [C@H]8CCNCC8.Cl
Molecular Formula
C40H37N5O.xHCl
Molecular Weight
713.144
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
KBH21037-HS 1x 96 Well
GENLISA Human Glycosylphosphatidylinositol Anchored High Density Lipoprotein Binding Protein 1 (GPIHBP1) ELISA
Sign In for Pricing
View Details 
EM1423 96 Tests
Mouse TRAb (Thyroid Stimulating Hormone Receptor Antibody) ELISA Kit
Sign In for Pricing
View Details bs-7786R-PerCP-Cy5.5 100 µL
CDCA2 Polyclonal Antibody, PerCP-Cy5.5 Conjugated
Sign In for Pricing
View Details 
47140061 1.0 µg DNA
TMPRSS11D Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details