Deltarasin HCl
Deltarasin is a high-affinity inhibitor that disrupts the PDEδ-KRAS interaction by occupying a hydrophobic pocket on PDEδ. This inhibition impairs KRAS signaling and cell growth in pancreatic cancer models, and its anti-cancer activity is enhanced when combined with autophagy blockade. It is used in oncology research to study KRAS-driven cancers in both cellular and animal studies.
Product Specifications
CAS Number
1440898-82-7
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
[C@H] (COC1=CC=C (C=C1) C=2N (CC3=CC=CC=C3) C=4C (N2) =CC=CC4) (N5C (=NC=6C5=CC=CC6) C7=CC=CC=C7) [C@H]8CCNCC8.Cl
Molecular Formula
C40H37N5O.xHCl
Molecular Weight
713.144
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-10316R-RBITC-TR 20 µL
DSPP Polyclonal Antibody, RBITC Conjugated
Sign In for Pricing
View Details 
abx306823-01 20 µg
Polymerase (DNA Directed), Alpha 2 (70 kDa Subunit) (POLA2) Antibody (Biotin)
Sign In for Pricing
View Details abx306823-02 50 µg
Polymerase (DNA Directed), Alpha 2 (70 kDa Subunit) (POLA2) Antibody (Biotin)
Sign In for Pricing
View Details abx306823-03 100 µg
Polymerase (DNA Directed), Alpha 2 (70 kDa Subunit) (POLA2) Antibody (Biotin)
Sign In for Pricing
View Details abx306823-04 200 µg
Polymerase (DNA Directed), Alpha 2 (70 kDa Subunit) (POLA2) Antibody (Biotin)
Sign In for Pricing
View Details abx306823-05 1 mg
Polymerase (DNA Directed), Alpha 2 (70 kDa Subunit) (POLA2) Antibody (Biotin)
Sign In for Pricing
View Details